The comedy, written by Tina Fey, came out 10 years ago at the end of April, and Lohan revealed that there are plans brewing to reunite the cast and crew for some kind of celebration.
"I saw Tina and she mentioned doing a reunion," the actress told host Jimmy Fallon. "She said she was talking to Lorne [Michaels] about it. She's talking to the big boss."
Lohan's already been part of a mini-"Mean Girls" get-together; last month, she posted an Instagram photo of herself hanging out with actors Daniel Franzese (Damian) and Rajiv Surendra (Kevin G).
But a mega reunion? How fetch would that be? (Yeah, we're still trying to make fetch happen.)
And for your viewing pleasure, Fallon throws water in Lohan's face:
[Photo by Theo Wargo/NBC/Getty Images for "The Tonight Show Starring Jimmy Fallon"]