Ephron, whose famous films include "Sleepless in Seattle," "You've Got Mail" and, of course, "When Harry Met Sally" passed away after a battle with leukemia at the age of 71 on June 26, 2012.
As a trailblazer in her field -- introducing the ubiquitous theory "Men and women can't be friends" -- Ephron is leading the way in a new special, "MAKERS," which spotlights remarkable women. The special will showcase "hundreds of compelling stories from women of today and tomorrow."
In the video above, Ephron speaks about her most famous flick, 1989's "When Harry Met Sally," and explains how the two titular characters are based on director Rob Reiner and Ephron herself.
"MAKERS" airs February 26 at 8 PM EST on PBS.
MORE 'MAKERS' Carrie Brownstein in 'Makers': Sleater-Kinney and the 'Female Band' Label Soul Surfer Bethany Hamilton Makes Her Mark in 'Makers' Documentary PBS Documentary 'Makers' Puts Spotlight On Danica Patrick 'The Makers': One Of NYC's First Female Firefighters Talks Of Hazing And Harassment [VIDEO] The Makers: Xerox CEO Ursula Burns Tells Her Story