The movie, directed by Judd Apatow, is the self-billed sort-of sequel to 2007's "Knocked Up." Here, Mann (Apatow's real-life wife) and Rudd return to deal with their marriage, their kids and, uh, bathroom behavior, as they both approach the dreaded 4-0. Along for the ride are their daughters, Sadie and Charlotte (played by Apatow and Mann's real-life children, Maude and Iris), as well as Pete's dad, Larry (Albert Brooks).
You can check out the newest clip from the movie above. "This Is 40," starring Rudd, Mann, Brooks and Melissa McCarthy, hits theaters on December 21, 2012. For more of the top films coming out this season, check out our 2012 Holiday Movie Preview in the gallery below.