After skeptics said it couldn't be done, the centuries-spanning "Cloud Atlas" finally took to the big screen for its world premiere.

Sci-fi vets Andy and Lana Wachowski ("The Matrix"), along with Tom Tykwer ("Run Lola Run"), adapted David Mitchell's ambitious novel. The starstudded cast -- Tom Hanks, Halle Berry, Hugh Grant, Jim Sturgess, and Susan Sarandon -- all do double duty (hexa-duty?) as they play out six story lines, which span time and space.

The film premiered at LA's Grauman's Chinese Theatre on Wednesday night. Take a look at all the stars -- including Keanu! -- below.

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