In 'The Dilemma,' Vince Vaughn discovers that his best friend's wife (Winona Ryder) is cheating on him and sets out to prove it.

But his plan isn't without a few bumps in the road -- and on the face. In this exclusive clip, which aired tonight at the People's Choice Awards, Vaughn rolls into some nasty foliage after seeing the adulterous couple kiss, resulting in some pretty bad side effects.

Queen Latifah also makes her mark, offering Vaughn some karate lessons from her personal trainer. (Doesn't look like he's game though.)

'The Dilemma' premieres January 14, 2011.

Vaughn's played a lot of funny men in his career. But, aside from this upcoming film, which do you think has been his best role?

What was Vince Vaughn's best role?
Gary in 'The Break Up'45 (9.8%)
Wes Mantooth in 'Anchorman'15 (3.3%)
Trent in 'Swingers'63 (13.7%)
Beanie in 'Old School'64 (13.9%)
Peter in 'Dodgeball'75 (16.3%)
Fred Claus in 'Fred Claus'16 (3.5%)
Norman Bates in 'Psycho'4 (0.9%)
Reese in 'Starsky and Hutch'3 (0.7%)
Luke Zoolander in 'Zoolander'3 (0.7%)
Jeremy in 'Wedding Crashers'173 (37.5%)