Ready to call it a wrap on all the year-end, best-of-2010 wrap-ups? Us too -- especially when 2011's shaping up to bring us a bevy of Next Big Things. Whether they're starring in reboots, remakes or really edgy indie flicks, the following six actors and actresses are poised to push through big-time by this time next year.

Of course, as much as we love laying bets on who will be the big box-office breakthroughs, we also admit that this is fingers-crossed speculation on our part. In fact, considering how Tom Hardy, our 2010 breakout-star pick, came out of nowhere in 'Inception' to take that title, we'll be just as happy to find in 12 months' time that we've been surprised yet again.

Emily Browning
Biggest Role in 2011: Baby Doll in 'Sucker Punch'
With scarce well-known credits under her belt heretofore, Oz-born actress Browning will likely sucker-punch American audiences with her out-of-nowhere lead role in 2011's badass chick flick 'Sucker Punch,' about a group of institutionalized girls plotting their way out of a 1950s mental asylum. Bonus: Her scenes opposite Guatamalan-born actor Oscar Isaac -- another exciting actor on the rise -- as Baby Doll's lobotomy-performing nemesis.

Michael Fassbender
Biggest Role in 2011: Magneto in 'X-Men: First Class'
He's been one of those "that guy" character actors for years, having appeared in '300,' 'Band of Brothers' and 'Inglourious Basterds.' In 2011, the German-born Fassbender, 33, will prove hard to forget. He'll capture the fancy of comic-book geeks as future mutant meanie Magneto in 'X-Men: First Class,' make ladies swoon as Mr. Rochester in 'Jane Eyre' and get audiences' blood a-pumping in Steven Soderbergh's action flick 'Haywire.'

Chris Hemsworth
Biggest Role in 2011: Thor in 'Thor'
When you're an Aussie actor best (if only) known stateside for your supporting part in 2009's 'Star Trek,' any role in 2011's 'Thor' would be a good get. Hemsworth, 27, landed the role as the fantasy flick's eponymous warrior, appearing alongside such A-listers as Anthony Hopkins and Natalie Portman. That puts Hemsworth squarely in the-next-Sam-Worthington territory -- and puts him in good company with fellow 'Thor' thespian Tom Hiddleston, the young London talent poised for a breakout of his own.

Jennifer Lawrence
Biggest Role in 2011: Mystique in 'X-Men: First Class'
In 2010, Lawrence was one of those rising stars who was heard of (for her incredible starring performance in 'Winter's Bone') but not seen. That'll be remedied next year, when she'll appear in a trifecta of buzzed-about films: the latest 'X-Men' installment, the teen flick 'Like Crazy,' and 'The Beaver,' Mel Gibson's much-anticipated comeback vehicle (which could have been subtitled 'Like Crazy').

Rooney Mara
Biggest Role in 2011: Lisbeth Salander in 'The Girl with the Dragon Tattoo'
In 2010's 'The Social Network,' she was the Girl With the Nerve to Dump Mark Zuckerberg -- a part she played so well, she may soon be the Girl With the Best Supporting Actress Nomination. In 2011's based on-the-bestseller 'The Girl With the Dragon Tattoo,' she'll appear in the title role as Lisbeth Salander, one of modern lit's most compelling and complicated heroines. Come 2012, she'll surely be one of Those Girls Who've Got Hollywood by a String.

Kenny Wormald
Biggest Role in 2011: Ren in 'Footloose'
Twenty-five years from now, perhaps we'll all be playing Six Degrees of Kenny Wormald. Thanks to his first-ever starring role -- as dance-happy Ren in 2011's 'Footloose' remake, the role originated by Kevin Bacon, in 1984 -- Wormald's name is already mentioned in the same breath as co-stars Dennis Quaid, Andie MacDowell and 'Dancing with the Stars' vet Julianne Hough (another up-and-comer whose part in 'Burlesque' places her just one degree from Cher). Let's hear it for the boy!