Cory Goodman (the upcoming adaptation of the Korean comic Priest) and Jeremy Lott have been hired by Mad Chance and Circle of Confusion (the upcoming Walking Dead television series) to pen the screenplay. No director or principal talent have been attached at this early stage, but the producers have told Borys Kit at Heat Vision that their hope is to turn Lore into a Men in Black-esque action-adventure franchise. That's not a bad goal to shoot for, but they'll certainly have competition; a few "elite team protect the world from hidden horrors" properties have risen lately, the most recent being Archangels, which Joseph Kosinski is set to direct for Scott Free Productions.
Judging by the fact that the hardcover premiere edition and first trade paperback are out of stock at IDW's official store, I'm guessing that not a lot of people have had a chance to discover the series for themselves. If you have read Lore, however, I'd love to know if you're looking forward to a film adaptation or if it's best left to the printed page.