SpliceThere are many great reasons to see Vincenzo Natali's Splice this weekend. First of all, it is an awesome movie, and I mean that in the most literal sense. My jaw dropped a number of times while I was watching Splice. It's visually stunning, eerie, extremely well written, and very, very smart. It's not just about a monster. It's about the humanity of this creature Dren, and, in turn, how she brings out the monstrous in her human creators. There's a reason Guillermo del Toro is on board as a producer, and it's because, as in all of his own films, the humans turn out to be as dangerous and unpredictable as their magnificent chimera.

In those jaw-dropping moments, I thought to myself, "Oh, they're not going to go there. They can't. This is a big studio movie. No way." But then it went there again and again and again. It pushes the boundaries just as its main characters, genius genetic scientists Clive (Adrien Brody) and Elsa (Sarah Polley), did by creating Dren, and just as great science fiction should.

I don't mean there were Human Centipede-style gross-outs – the trailers make it look a bit more like a horror movie than it really is. What is shown onscreen is truly thrilling, from the moment Dren skitters across the lab floor to, well, you'll just have to find out. And those moments might lose some audience members, but for those of us looking for something fresh, something smart, something unique, you will be mesmerized.

Warner Bros. is taking a big risk with Splice, and we speak with our dollars. Buy a ticket, take the ride, and maybe we'll see more intelligent, risky movies like Splice being supported by big studios in the future. For more on Splice, read Peter Hall's extensive interviews with co-writer and director Vincenzo Natali here and here, and Kevin Kelly's review of it from Sundance.