Start diving into those couch cushions for coin, devoted Trekkers, on June 27th you can start bidding on the above model of the U.S.S. Enterprise being strangled by some kind of serpentine space monster at Juliens Auctions. io9 has bigger pictures of the one-of-a-kind collectible as well as a gallery of even more Trek memorabilia, including some props from J.J. Abrams' recent foray into the franchise, that will be joining Rafael Burgos sculpture in the auction.
The auction will take place in the Planet Hollywood in Las Vegas, where William Shatner will be appearing in person to auction off some of his personal items, including a custom made motorcycle. If you can't make it to Vegas, however, it does look as though you can bid online as well. All proceeds will be going to good, charitable causes, though precisely where depends on whose item it is (those provided by Gene Roddenberry's estate will go to The Roddenberry Foundation, for example)
The official site for Julien's Auctions has a far more detailed list of what kind of gems we can expect from the event, while io9 helps dish out pictures of some of the goods.