Silver is the producer of Lobo as well as Holmes, and he says: "I don't think he's going to do it now. The studio wants us and Guy to focus on making another Sherlock Holmes. So, I think we're going to be doing that. But we're seeing what happens with this..." He goes on to talk about the first film's success, and how they're trying their darndest to get a sequel in the works. Since Lobo has been waiting around for ages (here is a news bite from 2006), one might assume he could just pick up the antihero biker afterwards, but Silver guesses that a new director will be picked instead. "It's all happening at once now."
It's not very surprising that Lobo is getting tossed aside. It wasn't too long ago that everyone was just about done with Ritchie's filmmaking, so now that his cinematic struggles are in the past and out of focus, who wouldn't want to enjoy the limelight for a little while longer before taking his next risk? But if you were dying for this combo, there's still a teeny bit of hope -- this isn't official news yet. But I'm betting it's only a matter of time.