Pajiba says yes, and they say that Peter Segal (Get Smart, Tommy Boy) is the director currently circling the long-dormant project. Director Robert Rodriguez (Shorts) was once enthusiastic about taking a crack at the material, but Warner Brothers wants to move on the project soon and Rodriguez keeps a full plate. Unlike Pajiba, though, I don't see this potential shift in directors as a huge step down.
Segal is studio-slick in a way that Rodriguez isn't, and I think he's better able to create a film that would appeal to both adults and kids. Rodriguez's The Jetsons would certainly be funky, but his family film output, while imaginative, is often too immature for grown-up tastes. I'm still hopeful about the project, despite the existence of two completely forgettable mega-budget Flintstones feature films, proving that I'm just a total nerd when it comes to Hanna-Barbera cartoons.