According to the actor, Afterlife will center on Alice, "...roaming the world looking for survivors and she's wound up in LA, which has been burning for three years. She comes across an LA jail surrounded be these half-dead, uhh... [Zombies] Anyway, she comes across the jail and there's a couple of survivors and she lands on top of the roof and partners up with me to fight the guys that are coming after them. We're trying to get all of the survivors out of the jail to safety." When asked about Miller's role, Kodje told Blackfilm that the Prison Break star will be, "...playing a guy that we actually locked up when we took over the jail because we weren't sure if he was one of them or not. He comes into play as we try to find a way to get out with our survivors" -- and I guess if you need a guy to engineer a jailbreak, Miller is really the only logical choice.
Resident Evil: Afterlife will start shooting in Toronto in the next couple of weeks, and is scheduled to arrive in theaters on September 27, 2010.