Could the same be said of Ben Stiller's forays into the fold? (*cough* Mystery Men) Not really. But would it help with Robert Downey Jr. and Tina Fey? Entertainment Weekly posts that both actors are looking into joining Stiller's animated villain film, Master Mind. (Christopher blogged about it here, last year.) The premise is simple. A villain accidentally kills the guy he's arching, and loses his will to live.
Having these two voices certainly sweetens the pot, but as we've learned after many years of disappointment -- amazing casts don't necessarily make even decent movies. It all comes down to the script (written by Alan Schoolcraft and Brent Simons), and Stiller's involvement. We'll have to wait and see.
Note: EW says that Cameron Hood and Kyle Jefferson are still on to direct, but Moviehole talked to a Dreamworks source who said that they left the project months ago. IMDb, meanwhile, says it's Gary Trousdale.